What is Gabapentin ?

Gabapentin is an anti-epileptic medication, also called an anticonvulsant. It affects chemicals and nerves in the body that are involved in the cause of seizures and some types of pain.

Gabapentin is used in adults to treat nerve pain caused by herpes virus or shingles (herpes zoster).

The Horizant brand of gabapentin is also used to treat restless legs syndrome (RLS).

The Neurontin brand of gabapentin is also used to treat seizures in adults and children who are at least 3 years old.

Use only the brand and form of gabapentin that your doctor has prescribed. Check your medicine each time you get a refill at the pharmacy, to make sure you have received the correct form of this medication.

DIN (Drug Identification Number)
02084260 Neurontin 100 mg capsule
02084279 Neurontin 300 mg capsule
02084287 Neurontin 400 mg capsule
02239717 Neurontin 600 mg tablet
02239718 Neurontin 800 mg tablet

Gabapentin, marketed under the brand name Neurontin among others, is a medication used to treat epilepsy, neuropathic pain, hot flashes, and restless leg syndrome.

In epilepsy it may be used for those with partial seizures. It is recommended as one of a number of first line medications for the treatment of neuropathic pain in diabetic neuropathy, post-herpetic neuralgia, and central neuropathic pain. For neuropathic pain about 14% of people have a meaningful benefit.

Common side effects include sleepiness and dizziness. Serious side effects may include an increased risk of suicide, aggressive behaviour, and drug reaction with eosinophilia and systemic symptoms. It is unclear if it is safe during pregnancy or breastfeeding.

Lower doses should be used in people with kidney problems. Gabapentin affects the inhibitory neurotransmitter γ-aminobutyric acid (GABA) but how it works is otherwise unclear.

Gabapentin was first approved for use in 1993.  The wholesale price is about 1.35 USD per day.  In the United States it has been available as a generic medicationsince 2004. As of 2015 the cost for a typical month of medication in the United States is 100 to 200 USD.

During the 1990s Parke-Davis, a sub-company of Pfizer, used a number of techniques to encourage physicians in the United States to use gabapentin for unapproved uses.

What form(s) does this medication come in?

Capsules

100 mg
Each hard gelatin Coni-Snap capsule, with white opaque body and cap printed with “PD” on one side and “Neurontin/100 mg” on the other, contains gabapentin 100 mg. Nonmedicinal ingredients: cornstarch, lactose, and talc; capsule shell: FD&C Blue No. 2, gelatin, red iron oxide, silicon dioxide, sodium lauryl sulfate, titanium dioxide, and yellow iron oxide.

300 mg
Each hard gelatin Coni-Snap capsule, with yellow opaque body and cap printed with “PD” on one side and “Neurontin/300 mg” on the other, contains gabapentin 300 mg. Nonmedicinal ingredients: cornstarch, lactose, and talc; capsule shell: FD&C Blue No. 2, gelatin, red iron oxide, silicon dioxide, sodium lauryl sulfate, titanium dioxide, and yellow iron oxide.

400 mg
Each hard gelatin Coni-Snap capsule, with orange opaque body and cap printed with “PD” on one side and “Neurontin/400 mg” on the other, contains gabapentin 400 mg. Nonmedicinal ingredients: cornstarch, lactose, and talc; capsule shell: FD&C Blue No. 2, gelatin, red iron oxide, silicon dioxide, sodium lauryl sulfate, titanium dioxide, and yellow iron oxide.

Tablets

600 mg
Each white, elliptical, film-coated tablet with “Neurontin 600” printed on one side contains gabapentin 600 mg. Nonmedicinal ingredients:ammonium hydroxide, black iron oxide, candelilla wax, copolyvidone, cornstarch, hydroxypropyl cellulose, magnesium stearate, poloxamer 407 NF, and talc.

800 mg
Each white, elliptical, film-coated tablet with “Neurontin 800” printed on one side contains gabapentin 800 mg. Nonmedicinal ingredients: candelilla wax, copolyvidone, cornstarch, hydroypropylcellulose, hypromellose, magnesium stearate, poloxamer 407 NF, red iron oxide, yellow iron oxide, and talc.

 

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