Suicide Trend of Taking Gabapentin

Gabapentin is used to treat painful nerve diseases.It is used to help control certain kinds of seizures.It may be given to you for other reasons. Talk with the doctor.

As with all antiepileptic drugs approved in the US, gabapentin label contains a warning of an increased risk of suicidal thoughts and behaviors.

This warning is based on a meta-analysis of all approved antiepileptic drugs in 2008, and not with gabapentin alone.

According to an experimental meta-analysis of insurance claims database, gabapentin use is associated with about 40% increased risk of suicide, suicide attempt and violent death as compared with a reference anticonvulsant drug topiramate. The risk is increased for people with bipolar disorder or epilepsy.

Another study has shown an approximately doubled rate of suicide attempts and self-harm in people with bipolar disorder who are taking gabapentin versus those taking lithium.

A large Swedish study suggests that gabapentinoids are associated with an increased risk of suicidal behaviour, unintentional overdoses, head/body injuries, and road traffic incidents and offences.

On the other hand, a study published by the Harvard Data Science Review found that gabapentin was associated with a significantly reduced rate of suicide.

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